hemorrhagic shock. Hemorrhage, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group: Group A receives 250 ml of hypertonic saline with a concentration of 5%, and then, according to standard treatments, isotonic saline with a concentration of 0.9% is
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: People with hemorrhagic trauma confirmed by a physician 18 years or older people In people exposed to penetrating or blunt trauma one hour before randomization In people with systolic blood pressure =100 mm Hg In people with informed consent regarding participation in the research In people with a decrease in blood volume (more than 1000 ml)
Exclusion criteria
Exclusion criteria: Patients with a history of high blood chloride Patients with a history of high sodium levels in the blood Patients with a history of high potassium levels in the blood Patients with a history of kidney dysfunction Patients with a history of pregnancy Patients with a history of epilepsy Patients with a history of blood coagulation-related diseases Patients with a history of liver disease Patients with a history of a severe decrease in body temperature to less than 28 degrees Celsius Patients with a history of inability to receive IV Patients with a history of absence of cardiac sinus rhythm Patients with a history of cardiac arrest Patients with a history of cardiopulmonary resuscitation Patients with a history of burns of more than 20% of the body surface Patients with a history of increased intracranial pressure Patients with a history of anaphylactic reactions Patients with tissue or cellular dehydration Patients with a history of receiving more than 2 liters of crystalloid before the study began Patients with a history of suffocation caused by hanging Patients transferred from other hospitals Patients with excessive delay in the treatment process
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of this study include a decrease in the mortality rate of patients due to hemorrhagic shock during the intervention period. Timepoint: Upon discharge. Method of measurement: Patient's File. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reducing the length of hospital stay. Timepoint: Upon discharge. Method of measurement: Patient's File.;Reducing the length of ICU stay. Timepoint: Upon discharge. Method of measurement: Patient's File.;Reducing the volume of blood and fluids received. Timepoint: After intervention. Method of measurement: Check list and patient's file. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Sadegh Ahmadi Rashti
Bandare-abbas University of Medical Sciences
Outcome results
None listed