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Determining and comparing the effect of Clotrimazole vaginal cream and vaginal cream (Jashir plant) on candidal vulvovaginitis

Determining and comparing the effect of Clotrimazole vaginal cream and Prongus Fluorase vaginal cream (Jashir plant) on candidal vulvovaginitis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230521058245N1
Enrollment
104
Registered
2023-06-27
Start date
2023-06-25
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candidal vulvovaginitis. Candidiasis of vulva and vagina

Interventions

Intervention 1: Intervention group:Intervention group: Jashir vaginal cream for one week, one 5 mg applicator every night at bedtime vaginally. Intervention 2: Control group: Clotrimazole vaginal crea

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women of reproductive age (15 to 45 years) Being married Having at least two symptoms of cheesy secretions and itching Least a Sobel score of 4 Positive culture

Exclusion criteria

Exclusion criteria: Failure to participate in the study Lactating women Menopausal women Menstruation Pregnant women Having diabetes Women with immunodeficiency and immunosuppressive diseases Suffering from other vaginal infections and sexually transmitted infections Frequent and recurring candidal vulginitis History of allergy to Jashir

Design outcomes

Primary

MeasureTime frame
Although vaginitis is a candidate. Timepoint: Before the start of the intervention and 7 days after the end of the intervention. Method of measurement: The score obtained from Sobel clinical semi-quantitative system.;Dysparonychia due to candidal vulvovaginitis. Timepoint: Dysparonychia due to candidal vulvovaginitis. Method of measurement: Visual Analogue Scale.;Burning of the vulva and vagina. Timepoint: before the start of the intervention and 7 days after the end of the intervention. Method of measurement: Visual Analogue Scale.;White cheesy discharge. Timepoint: before the start of the intervention and 7 days after the end of the intervention. Method of measurement: According to the score obtained from the Sobel scoring system.;Edema vulva. Timepoint: before the start of the intervention and 7 days after the end of the intervention. Method of measurement: According to the score obtained from the Sobel scoring system.;Itching of the vulva and vagina. Timepoint: before the start of the intervention and 7 days after the end of the intervention. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Improvement of candidal vaginitis. Timepoint: 7 days after the end of the intervention. Method of measurement: Removal of symptoms and signs at the beginning and total Sobel severity score = 2 and negative culture.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Hekmatzadeh

Yasouj University of Medical Sciences

sf.hekmatzadeh@yahoo.com+98 74 3323 5145

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026