Opioid related disorders in pediatric intensive care unit. Opioid related disorders
Conditions
Interventions
Intervention 1: Intervention group:In this group, patients will be anesthetized with 0.1 milligram per kilogram of intravenous Midazolam and 1 (or more) micrograms per kilogram of Fentanyl along with
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 12 Years
Inclusion criteria
Inclusion criteria: Age 1 year to 12 years Admission to pediatric intensive care unit (PICU) Under mechanical ventilation and sedation
Exclusion criteria
Exclusion criteria: Children receiving Barbiturates Persistent bradycardia (less than 5th percentile of normal for age) Hypotension (less than 5th percentile of normal age) Cardiac arrhythmia Involvement of the central nervous system (brain trauma, encephalitis, meningitis...)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determining and comparing the needed total Fentanyl dose in each group. Timepoint: From enrollment up to seven days. Method of measurement: Dose counting.;Determining and comparing the needed total Midazolam dose in each group. Timepoint: From enrollment up to seven days. Method of measurement: Dose counting. | — |
Secondary
| Measure | Time frame |
|---|---|
| Determining the need for a second sedative drug in each group. Timepoint: From enrollment up to seven days. Method of measurement: Patient file.;Determining the need for the third sedative drug in each group. Timepoint: From enrollment up to seven days. Method of measurement: Patient file.;Determining the need for the muscle relaxant in each group. Timepoint: From enrollment up to seven days. Method of measurement: Patient file. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNajmeh Forouzan
Shahid Beheshti University of Medical Sciences
Outcome results
None listed