Patienst with severe chronic periodontitis. Chronic periodontitis, generalized
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: patients with severe periodontitis Patients must be systemically healthy, Class I dental category Subjects with deep vertical periodontal lesions (>6 mm) showing no radiographic crestal alveolar lamina dura
Exclusion criteria
Exclusion criteria: Presence of any disease or medication that alters the immune system or interferes with healing ability Smokers (more than 10 cigarettes per day) Pregnant or nursing mothers because hormonal factors may influence the condition. Allergies or adverse reactions to valacyclovir Patients with renal impairment or reduced renal function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pocket Depth. Timepoint: baseline- 3 and 6 months after the intervention. Method of measurement: Michigan O periodontal probe.;Bleeding on probing. Timepoint: baseline 3 and 6 months after the intervention. Method of measurement: michigan O periodontal probe. | — |
Secondary
| Measure | Time frame |
|---|---|
| Radiographic change in lamina dura bone. Timepoint: baseline and 6 months after intervention. Method of measurement: Panoramic radiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Mashhad University of Medical Sciences