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Comparison of the Effect of Pethidine and Dexmedetomidine on Relieving Shivering after Cesarean Section

Comparison of the Effect of Pethidine and Dexmedetomidine on Relieving Shivering after Cesarean Section under Spinal Anesthesia in Patients that Received Misoprostol

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230518058225N4
Enrollment
80
Registered
2024-06-16
Start date
2024-07-05
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean. Delivery by caesarean section, unspecified

Interventions

Intervention 1: Intervention group1: Five minutes after delivery, if the patient still shows significant tremors (grade 3 or 4 on the tremor scale), 0.3 ml of dexmedetomidine with a concentration of 1

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant women The age range of 18 to 45 years A person with normal health A person with mild systemic disease Candidate for caesarean section who underwent spinal anesthesia and received mesoprostol experienced chills (grade 3 or 4 according to Crossley and Mahajan scale).

Exclusion criteria

Exclusion criteria: A history of spine surgery Having any contraindications for spinal anesthesia Emergency cesarean delivery Weight less than 60 kg or more than 120 kg Known hypersensitivity to dexmedetomidine or pethidine Heart, kidney or liver disease that requires follow-up or drug use. Pre-eclampsia General anesthesia Combined spinal-epidural anesthesia

Design outcomes

Primary

MeasureTime frame
Shivering. Timepoint: From the moment of entering the operating room until the end of delivery. Method of measurement: Using the Crossley and Mahajan five-level scale (grade 0: no shivering, grade 1: one or more of the following: piloarection, peripheral vasoconstriction, peripheral cyanosis, but no visible muscle activity, grade 2: visible muscle activity limited to One muscle group grade 3: visible muscle activity in more than one muscle group grade 4: large muscle activity that involves the whole body).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Aklamli

Iran University of Medical Sciences

Aklamli.m@iums.ac.ir+98 21 5560 6033

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026