The effect of intravenous administration of atracurium by the preparation method with intravenous injection of atracurium with presleep method with intravenous administration of rocuronium in the optimal time of intubation

Comparison of the effect of intravenous administration of atracurium by preparation method with intravenous injection of atracurium with presleep method with intravenous administration of rocuronium at the optimal time of intubation in induction of anesthesia by rapid sequence method using muscle nerve relaxation monitoring

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230518058225N2

Enrollment

Registered

2024-03-23

Start date

2024-04-02

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intubation. Failed or difficult intubation

Interventions

Intervention 1: Intervention group 1: In the Prehypnotic group, At first intravenous midazolam with a concentration of one milligram per cc (with an amount of 40 micrograms per kilogram of body weight

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Candidate patients for non-emergency surgery, under general anesthesia for more than 120 minutes Age between 18-50 years Malampathi 1 and 2 A person with normal health A person with mild systemic disease

Exclusion criteria

Exclusion criteria: Allergy to the drugs used in the plan History of asthma Anxiety Hemodynamic instability Addiction Heart disease Lung disease Active cancer Taking tetracycline, gentamicin, magnesium and other drugs that aggravate muscle relaxation

Design outcomes

Primary

Measure	Time frame
The time required from the moment of drug injection until the muscles relax. Timepoint: Continuously from the moment the drug is injected until the muscles relax and the PTC (muscle condition monitoring device) shows zero. Method of measurement: Measuring with a stopwatch based on seconds.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPooya Derakhshan

Iran University of Medical Sciences

pooyaderakh@yahoo.com+98 21 6435 2533

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026