Overactive bladder, Urinary incontinence. Other specified disorders of urinary system
Conditions
Interventions
Intervention 1: Intervention group 1: The treatment group includes the mirabegron treatment group, 142 people will be allocated to this group. Randomization of participants will be done using block ra
However, the assessor of the patients' symptoms will be unaware of their treatment group (single blind). The first group will be treated with Mirabegron (Tasnim Gostar Company, made in Iran) 50 mg dai
However, the assessor of the patients' symptoms will be unaware of their treatme
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Diagnosis of OAB by a gynecologist based on the following criteria: Urination more than eight times in a 24 hour period, Urinary urgency with or without urge incontinence, aged 20-70 years, Providing written informed consent.
Exclusion criteria
Exclusion criteria: Active urinary tract infection, pregnancy, breastfeeding or less than 6 months after giving birth, history of surgery to treat incontinence or pelvic prolapse, fecal incontinence or spinal cord lesions, serious illnesses: cancer, Kidney, heart, lung disease, diabetes, epilepsy or history of seizures, uncontrolled blood pressure, rheumatism, physical disabilities, dementia or severe psychiatric disorders, drug, alcohol or tobacco use Unwillingness or inability to follow treatment, occurrence of serious drug side effects (especially to anticholinergics), presence of anatomical abnormalities resulting from surgery in the urinary system (ductal stricture, prolapse, obstructive tumor, fibrosis after radiation therapy, trauma, or iatrogenic surgery), Dysfunction of the lower nervous system of the bladder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary frequency. Timepoint: Prior to intervention. Method of measurement: Standard Urinary Incontinence Questionnaire and Flowmetry.;Body Mass Index(BMI). Timepoint: Prior to intervention. Method of measurement: Standard urinary incontinence questionnaire and testing Urodynamic. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNarges Aghaesmaeili
Tehran University of Medical Sciences
Outcome results
None listed