teeth with with irreversible pulpitis. Pulpitis
Conditions
Interventions
Intervention 1: Intervention group: Suggested root canal treatment intervention using 1 million cord stem cells in 300 microliters of fibrin hydrogel containing 300 micrograms of exosome and growth f
Sponsors
University of San Francisco
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients must be systemically healthy, Class I dental category Involved teeth must have no periodontal disease detectable by periodontal examination. Patients must present with radiographic signs of endodontic disease (i.e., necrotic pulp with periapical radiolucency) One-rooted teeth number ?, ? and ? with irreversible pulpitis (need root canal treatment)".
Exclusion criteria
Exclusion criteria: Presence of any disease or medication that alters the immune system or interferes with healing ability Smokers (more than ?? cigarettes per day) External or internal tooth resorption Tooth perforation from the pulp cavity through the tip of the root exposing the tissue to material in the oral cavity. Pregnant or nursing mothers because hormonal factors may influence the condition. Allergies or adverse reactions to local anesthetic medications Patients under the age of ?? Patients with an ASA Classification II or higherI. Cardiovascular Disease Disable or mental illness Osteoporosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Radiographic observations. Timepoint: Before the intervention and 1 week, 3 months and 6 months after the intervention. Method of measurement: Radiographic observations.;Examination of signs of apical healing and dental vital signs. Timepoint: Before the intervention and 1 week, 3 months and 6 months after the intervention. Method of measurement: Routine dental vital test methods. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNeda Bayat
Tehran University of Medical Sciences
Outcome results
None listed