Skip to content

The comparative study of intravenous Ondansetron and Dexamethasone effects on reducing the incidence of postspinal anesthesia hypotension in elderly patients undergoing urologic surgeries

The comparative study of intravenous Ondansetron and Dexamethasone Effects on Reducing the Incidence of PostSpinal Anesthesia Hypotension in Elderly Patients Undergoing Urologic Surgeries

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230513058164N1
Enrollment
120
Registered
2023-05-18
Start date
2022-11-11
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Post spinal hypotension in elderly patients. Condition 2: Post Spinal Bradycardia. Hypotension Bradycardia, unspecified

Interventions

Intervention 1: Intervention Group A : Ondansetron Amp 4mg ,slow iv , Single Dose? 5 minutes prior to Spinal Anesthesia. Intervention 2: Intervention Group B: Dexamethasone Amp 8mg iv , Single Dos

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 65 years of age or more American Society of Anesthesiologists (ASA) physical status EF>40% Patients who do not have a contraindication for spinal anesthesia (such as coagulation disorder, thrombocytopenia ) Not allergic to local anesthetic No allergy to ondansetron or dexamethasone Not taking drugs related to steroids or serotonin (for example, selective serotonin reuptake inhibitors) Not suffering from uncontrolled cardiovascular, kidney, liver and thyroid diseases

Exclusion criteria

Exclusion criteria: Study Confounding Items Such as: Occurrence of Surgical Complications Such as Bleeding Hemodynamic Instability

Design outcomes

Primary

MeasureTime frame
Systolic Blood Pressure. Timepoint: 5 minutes before and 30 minutes following Spinal Anesthesia . Method of measurement: Sphygmomanometer.;Diastolic Blood Pressure. Timepoint: 5 minutes before and 30 minutes following Spinal Anesthesia. Method of measurement: Sphygmomanometer.;Heart Rate. Timepoint: 5 minutes before and 30 minutes following Spinal Anesthesia Procedure. Method of measurement: Pulse Oximeter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Tork

Yasouj University of Medical Sciences

aban253@gmail.com+98 21 4424 7963

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026