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Effect of Stimulation along with Affective Expectations Manipulation on Anhedonia

Effect of Transcranial Direct Current Stimulation along with Affective Expectations Manipulation on Affective Experience and Anhedonia among Anhedonic Patients Suffering from Major Depression Disorder

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230513058161N2
Enrollment
45
Registered
2023-08-11
Start date
2023-06-22
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depression Disorder. Severe depressive episode without psychotic symptoms

Interventions

Intervention 1: Intervention group 1: transcranial direct current stimulation and then induction of positive emotions. In this group, the participants first receive electrical stimulation through one

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Obtaining the initial diagnosis of major depressive disorder with anhedonia using a structured clinical interview and questionnaire. The patient should be able to perform the behavioral test and answer the questionnaires.

Exclusion criteria

Exclusion criteria: The presence of comorbid disorders such as substance abuse, psychotic disorders, bipolar disorder, anxiety disorders, and psychotic symptoms. The presence of metal parts in the head

Design outcomes

Primary

MeasureTime frame
Anhedonia. Timepoint: Before and after the intervention. Method of measurement: Positive Valence Systems Scale-21 questionnaire.

Secondary

MeasureTime frame
Probabilistic reward. Timepoint: Before and after the intervention. Method of measurement: Probabilistic reward task.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayeh Daneshvar

Shiraz University of Medical Sciences

somayedaneshvar@sums.ac.ir+98 71 3647 9080

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026