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The effect of treatment with escitalopram on quality of life and hospitalization rate in depressed patients with systolic heart failure

The effect of treatment with escitalopram on quality of life and hospitalization rate in depressed patients with systolic heart failure: a double blind randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230510058142N1
Enrollment
84
Registered
2023-12-09
Start date
2023-05-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure. Heart failure

Interventions

Intervention 1: Intervention group: Taking 20 mg of es citalopram orally, manufactured by abidi company, for 8 weeks from the beginning of the study then Refer to a psychiatrist after the end of the

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: People aged 30 to 75 years Patients with left ventricular systolic dysfunction (left ventricular ejection fraction <0.40) Clinical diagnosis of heart failure with at least one episode of dyspnea either with minimal activity or at rest NYHA classIII or IV Informed consent of patients

Exclusion criteria

Exclusion criteria: Previous history of intolerance to SSRI antidepressants Bipolar or severe personality disorder Severe suicidal thoughts Recent dependence on alcohol or drugs pregnancy breastfeeding

Design outcomes

Primary

MeasureTime frame
Quality of life. Timepoint: At the beginning of the study and 8 weeks later. Method of measurement: Minnesota Standard Questionnaire.

Secondary

MeasureTime frame
Hospitalization rate. Timepoint: The beginning of the study and 2 month later. Method of measurement: Patient files and Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactfarnaz pourrajab

Shahid Beheshti University of Medical Sciences

farnazpourrajab71@gmail.com+98 21 7343 3000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026