The effect of Repetitive transcranial magnetic stimulation (r-TMS) in the Dorsolateral Prefrontal Cortex (DLPFC) on the symptoms of patients with obsessive-compulsive disorder

The effect of Repetitive transcranial magnetic stimulation (r-TMS) in the Dorsolateral Prefrontal Cortex (DLPFC) on the symptoms of patients with obsessive-compulsive disorde

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230508058128N1

Enrollment

Registered

2023-05-10

Start date

2023-05-15

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-compulsive disorder. Obsessive-compulsive disorder

Interventions

Intervention 1: Intervention group: standard drug treatment + treatment using magnetic stimulation of the brain with rTMS device - during 4 weeks treatment with magnetic stimulation of the brain with

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Definitive diagnosis of OCD based on the DSM V diagnostic criteria by two psychiatrists (clinical interview) obtaining a score equal to or greater than 16 from the Y-BOCS questionnaire, not taking related drugs in the last four weeks and starting drug treatment with sertraline 150 mg (simultaneously to along with r-TMS for the intervention group), not receiving ECT in the past 6 months and the willingness of the subjects to participate in the research

Exclusion criteria

Exclusion criteria: Existence of accompanying psychiatric disorder, especially depression (based on Beck Depression Scale) score of Beck Questionnaire above 10, suffering from seizures use of drugs and substances, presence of metal implants, pacemaker, trauma or head injury and neurosurgery procedures incompleteness of patients data more than 10%

Design outcomes

Primary

Measure	Time frame
Yale-Brown Obsession Scale. Timepoint: Before the start of the study, after each RTMS session, 3 months after the last session. Method of measurement: Using a standard questionnaire.	—

Secondary

Measure	Time frame
Quality of Life Brief Version (WHOQOL-BREF). Timepoint: Before the intervention, after each session, 3 months after the last session. Method of measurement: Based on a standard questionnaire.;Symptoms of obsession. Timepoint: Before the intervention, after each session, 3 months after the last session. Method of measurement: Based on a standard questionnaire.;Beck depression questionnaire 2. Timepoint: Before the intervention, after each session, 3 months after the last session. Method of measurement: Based on a standard questionnaire.	—

Measure

Time frame

Quality of Life Brief Version (WHOQOL-BREF). Timepoint: Before the intervention, after each session, 3 months after the last session. Method of measurement: Based on a standard questionnaire.;Symptoms of obsession. Timepoint: Before the intervention, after each session, 3 months after the last session. Method of measurement: Based on a standard questionnaire.;Beck depression questionnaire 2. Timepoint: Before the intervention, after each session, 3 months after the last session. Method of measurement: Based on a standard questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Rajabi Bahabadi

Kerman University of Medical Sciences

rajabizhra68@gmail.com+98 34 3211 6330

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026