The effect of dexamethasone, droperidol and ginger on controlling nausea and vomiting

Evaluation of the prophylactic effect of dexamethasone and droperidol in comparison with dexamethasone and ginger on nausea and vomiting in patients undergoing laparoscopic cholecystectomy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230506058101N1

Enrollment

152

Registered

2023-05-31

Start date

2023-06-10

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystitis. Cholecystitis

Interventions

Intervention 1: Intervention group: In group A, 8 mg of intravenous dexamethasone and 75 µg/kg droperidol and 4 oral capsules of flour are given as a placebo instead of 4 oral ginger capsules before i

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidates for laparoscopic cholecystectomy who will be electively referred to Amir al-Momenin and Valiasr Arak hospitals Age range between 18-65 years ASA anesthesia class I, II Candidates for general anesthesia All candidate patients for laparoscopic cholecystectomy who undergo surgery Not being allergic to droperidol and ginger The duration of surgery between 60-150 minutes

Exclusion criteria

Exclusion criteria: Sensitivity to Droperidol and Ginger

Design outcomes

Primary

Measure	Time frame
Vomiting score during recovery. Timepoint: 2, 4, 8 and 12 hours after surgery. Method of measurement: Vomiting scoring checklist.;Nausea. Timepoint: in post-operative recovery. Method of measurement: Ask the patient.;Shivering. Timepoint: in post-operative recovery. Method of measurement: Ask the patient.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Mozafary Jalal

Arak University of Medical Sciences

www.atefehmozaffari45@gmail.com+98 86 3313 6055

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026