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Evaluation of the effectiveness of transcranial direct current stimulation (tDCS) in patients with substance abuse

Evaluation of the effectiveness of transcranial direct current stimulation (tDCS) on the level of craving and quality of life of patients with substance-use disorders

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230430058029N1
Enrollment
60
Registered
2023-05-29
Start date
2023-06-19
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: substance use disorder. Condition 2: Other stimulant dependence. Opioid dependence Other stimulant dependence

Interventions

Intervention 1: The first intervention group is treated daily with cathodic TDCS method in the first 15 sessions, and after 5 days of rest, they are treated with Sham in the next 15 sessions.Active tr
its weight is 5.1 kg In this study, 3 cathode leads and 3 anode leads are used. Each probe has two poles, positive and negative(3 cathode probes and 3 anode probes) has a cross-sectional area of 4 cm

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: patients with opioid or methamphetamine substance use disorders (based on DSM-5 criteria).

Exclusion criteria

Exclusion criteria: Taking anticonvulsiant drugs in the last 6 months Having neurological diseases Pregnancy Mental retardation Presence of a complication in the skull Presence of any metal in the skull or brain

Design outcomes

Primary

MeasureTime frame
The amount of craving. Timepoint: 6 months.During the follow-up period, patients will be evaluated for substance use in three stages of 1 month, 3 months and 6 months. Method of measurement: Addiction Craving Scale (ACS) questionnaire.

Secondary

MeasureTime frame
Quality of life. Timepoint: Before the intervention and in the follow-up period of 1 month, 3 months and 6 months. Method of measurement: SF-36 questionnaire score.;Data of EEG. Timepoint: Before the intervention and in the follow-up period of 1 month, 3 months and 6 months. Method of measurement: Brain signal processing.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKiomars Najafi

Rasht University of Medical Sciences

k_najafi@gums.ac.ir+98 13 3366 6268

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026