The effect of endoscopic treatments in the treatment of benign esophageal stricture

Comparing the effects of bougie, Balloon dilatation and incisional therapy on dysphagia in patients with benign esophageal stricture secondary to caustic injury

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230425057990N2

Enrollment

Registered

2023-11-14

Start date

2023-11-22

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

benign esophageal stricture. Esophageal obstruction

Interventions

Intervention 1: Intervention group: bougie-For this group of patients, we start with 7 to 9 mm bougie. Then, according to the response to the treatment, we increase the size of the bogie up to 13-15 m

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Unable to swallow Difficulty to swallow Benign esophageal stricture secondary to caustic injury

Exclusion criteria

Exclusion criteria: achalasia Untreated reflex Esophageal surgery during the last month Patients needing surgery

Design outcomes

Primary

Measure	Time frame
Technical success. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: Based of lumen diameter with residual stenosis less than 30%.;Technical success. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: Improvement of dysphagia symptoms.	—

Secondary

Measure	Time frame
Generic Quality of life. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: EuroQol-5D (EQ-5D) index.;Physically quality of life. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: body mass index.;Complication. Timepoint: up to 6 hours after the intervention. Method of measurement: Physical examination and history.	—

Measure

Time frame

Generic Quality of life. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: EuroQol-5D (EQ-5D) index.;Physically quality of life. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: body mass index.;Complication. Timepoint: up to 6 hours after the intervention. Method of measurement: Physical examination and history.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRamyar Zaman Golzari

Shahid Beheshti University of Medical Sciences

ramyar.golzari@gmail.com+98 21 2243 2525

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026