Effect of ultra-low dose Naloxone on pain

Effect of ultra-low dose Naloxone on pain intensity after laparoscopic cholecystectomy surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230424057986N1

Enrollment

Registered

2023-05-18

Start date

2023-06-05

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystitis. Cholecystitis

Interventions

Intervention 1: Intervention group: Intervention group: Patients with a specific anesthesia protocol that includes midazolam 0.1 mg/kg (manufacturer: Abu Rayhan), fentanyl 3 µg/kg (manufacturer: Norma

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate for non-emergency laparoscopic cholecystectomy surgery Age between 30-65 years

Exclusion criteria

Exclusion criteria: History of psychological illness Pregnant women Abuse of alcohol or drugs

Design outcomes

Primary

Measure	Time frame
Severity of patients' pain. Timepoint: 2, 6, 12 and 24 hours after surgery. Method of measurement: Based on numerical rating scale of pain (NRS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Habibi

Iran University of Medical Sciences

farshad.9.h@gmail.com+98 21 6693 5613

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026