Evaluation of the effect of local injection of tranexamic acid on bleeding during surgery

Evaluation of the effect of local injection of tranexamic acid on bleeding during surgery in patients with cleft palate

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230424057979N1

Enrollment

Registered

2023-05-01

Start date

2023-05-05

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cleft Palate. Cleft palate

Interventions

Intervention 1: Intervention group: the prepared medicine (10 mg/kg tranexamic acid) is injected locally to the patient half an hour before the operation along with 1 normal saline solution in 200,000

Eligibility

Sex/Gender

All

Age

8 Months to 60 Months

Inclusion criteria

Inclusion criteria: Children between 8 to 60 months Cleft Palate

Exclusion criteria

Exclusion criteria: Cleft Lip

Design outcomes

Primary

Measure	Time frame
The amount of bleeding during surgery. Timepoint: During surgery. Method of measurement: Quantitative criterion (the result of the difference in the weight of the accumulations of the suction glasses and the volume of the solution used for washing) and cumulative bleeding in gas pellets (the result of the difference in the weight of blood gases from the weight of the same amount of dry gas) and the qualitative Boezaart criterion.	—

Measure

Time frame

The amount of bleeding during surgery. Timepoint: During surgery. Method of measurement: Quantitative criterion (the result of the difference in the weight of the accumulations of the suction glasses and the volume of the solution used for washing) and cumulative bleeding in gas pellets (the result of the difference in the weight of blood gases from the weight of the same amount of dry gas) and the qualitative Boezaart criterion.

—

Secondary

Measure	Time frame
Surgeon satisfaction. Timepoint: After Surgery. Method of measurement: By Likert scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdi Karami

Iran University of Medical Sciences

dr.m.karami@gmail.com+98 21 8871 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026