Male Infertility. Male infertility
Conditions
Interventions
Intervention 1: Intervention group: They will receive melatonin drug with a dose of 5 mg (obtained from Hakim Pharmaceutical Company), one hour before sleep for 2 months. Intervention 2: Control group
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Men aged 18 to 45 with a history of infertility for at least one year Having a disorder in the spermogram with an unknown cause based on the criteria of the World Health Organization No underlying disease No history of chemotherapy Normality of gonadotropins Testosterone and prolactin Having a BMI less than 30
Exclusion criteria
Exclusion criteria: Azoospermia and the presence of chromosomal disorders such as Kleinfelter Taking chemical drugs during study Taking antioxidant supplements in the last three months Having intense physical activity Taking drugs that stimulate the sexual system or disrupt sex hormones. Genital infections Infectious diseases characterized by fever and leukocytosis. Infertility in wife and abnormal urology examination
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of spermogram test. Timepoint: Before the start of the intervention and three months after the treatment. Method of measurement: Semen analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in FSH. Timepoint: Before the start of the intervention and three months after the treatment. Method of measurement: Laboratory (hormone measurement, relevant techniques for each test).;Changes in LH. Timepoint: Before the start of the intervention and three months after the treatment. Method of measurement: Laboratory (hormone measurement, relevant techniques for each test).;Changes in testosterone levels. Timepoint: Before the start of the intervention and three months after the treatment. Method of measurement: Laboratory (hormone measurement, relevant techniques for each test). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Akbari
Babol University of Medical Sciences
Outcome results
None listed