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Investigating the effect of ketamine in pain control after cesarean section

The effect of Different Doses and side effects of Ketamin for Pain Control after Cesarean Section Surgery in Patients with Spinal Anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230417057937N1
Enrollment
120
Registered
2023-08-12
Start date
2023-08-23
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-surgery pain. Other complications of anaesthesia during labour and delivery

Interventions

Intervention 1: The first intervention group: Ketamine is initially given as a bolus dose of 0.25 mg/kg and then as a continuous infusion of 0.125 mg/kg during the operation. Intervention 2: The secon

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Having a term pregnancy and ASA(American Society of Anesthesiologists) class I, II Participants in the study should refer electively for caesarean section Consent to participate in the study Absence of any underlying diseases Absence of any mental illnesses or mental disorders

Exclusion criteria

Exclusion criteria: The presence of one of the diseases associated with pregnancy, such as gestational blood pressure or gestational diabetes and fetal problems. Allergy to ketamine or similar drugs BMI above 30

Design outcomes

Primary

MeasureTime frame
Comparison of postoperative pain scores in patients receiving intravenous ketamine and the group receiving normal saline. Timepoint: 0, 30, 60, 90, 120 minutes and 4, 6, 12, 24 hours after cesarean ???????. Method of measurement: Analogue Scale Visual.

Secondary

MeasureTime frame
Determining the relative frequency of hallucinations in the group receiving intravenous ketamine. Timepoint: 20 minutes after receiving the first dose of medicine. Method of measurement: Based on questions from the patient.;The time required for pain medication after the completion of spinal anesthesia. Timepoint: The first 24 hours after cesarean section. Method of measurement: Time of drug administration.;Apgar score of the newborn. Timepoint: The first and fifth minutes after birth. Method of measurement: It includes 5 components: heart rate, respiratory effort, muscle tone, reflex excitability, color.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmin Rabiei

Shahre-kord University of Medical Sciences

aminrabiei1997@gmail.com+98 38 3452 3824

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026