Evaluation of the effect of maintenance serum with the amount of sodium at the limit of isotonic saline on sodium level, blood pressure and acidosis in admitted patients.

Evaluation of the effect of maintenance serum with the amount of sodium at the limit of isotonic saline on sodium level, blood pressure and acidosis in PICU patients of Tehran Bahrami Children's Hospital

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230414057904N1

Enrollment

Registered

2024-01-10

Start date

2022-03-25

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Hypertension. Condition 2: Influence of the maintenance fluid (normal vs. half saline) on blood sodium level. Other secondary hypertension Hypo-osmolality and hyponatremia

Interventions

Intervention 1: Normal saline maintenance fluid, 4cc/kg.h for first 10kg, 2cc/kg.h for second 10kg, and 2cc/kg.h for third and more 10kg. There is no specific brand to use and it will depend on Bahram

Eligibility

Sex/Gender

All

Age

3 Months to 18 Years

Inclusion criteria

Inclusion criteria: Age between 3 months and 18 years Need for injectable serum

Exclusion criteria

Exclusion criteria: Sodium level below 130 mmol/L Sodium level above 150 mmol/L Having diabetes insipidus Diabetic ketoacidosis Kidney disease requiring dialysis Suffering from the disease of high sodium urinary excretion(Addison's disease, congenital adrenal hyperplasia, Barrett's syndrome) Patients before or after neurosurgery Require chemotherapy hydration Severe liver disease Patients who are likely to receive maintenance serum for less than 6 hours

Design outcomes

Primary

Measure	Time frame
?Blood Sodium level. Timepoint: 6,24,48, and 72 hours. Method of measurement: Blood lab test, with the same kit for all patients.;Blood pressure. Timepoint: Every hour. Method of measurement: Non-invasive blood pressure monitoring, with appropriate cuff size.;Blood PH. Timepoint: hours 6? 24? 48 , 72. Method of measurement: Blood lab test, with the same kit for all patients.;Blood bicarbonate level. Timepoint: hours 6? 24? 48 , 72. Method of measurement: Blood lab test, with the same kit for all patients.	—

Measure

Time frame

?Blood Sodium level. Timepoint: 6,24,48, and 72 hours. Method of measurement: Blood lab test, with the same kit for all patients.;Blood pressure. Timepoint: Every hour. Method of measurement: Non-invasive blood pressure monitoring, with appropriate cuff size.;Blood PH. Timepoint: hours 6? 24? 48 , 72. Method of measurement: Blood lab test, with the same kit for all patients.;Blood bicarbonate level. Timepoint: hours 6? 24? 48 , 72. Method of measurement: Blood lab test, with the same kit for all patients.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaezeh Jahanshahi

Tehran University of Medical Sciences

faezehjahanshahi@gmail.com+98 21 2244 2920

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026