Investigating the effect of evening primrose oil on reducing the severity of headache and disability due to menstrual migraine

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230409057857N1

Enrollment

Registered

2023-05-02

Start date

2023-05-31

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

menstrual migraine. Menstrual migraine, not intractable

Interventions

Intervention 1: Intervention group: intervention group receives common treatments (including sodium valproate 200 mg twice a day and nortriptyline 25 mg daily) along with 2 pearls 1000 mg evening prim

Eligibility

Sex/Gender

Female

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Age 18 to 55 years old Certain menstrual migraine diagnosed based on IHS classification and the neurologist opinion Not using other drugs (psychoactive and opiate ) Not suffering from another chronic illness except migraine Getting informed consent

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of headache and degree of disability caused by menstrual migraine. Timepoint: Before the intervention, 3 months after the intervention. Method of measurement: Visual Analogue Scale, Migraine Disability Assessment.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzaneh Mohammadi

Arak University of Medical Sciences

farzane.mo.1998@gmail.com+98 86 3417 3036

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026