gastric intestinal metaplasia.
Conditions
Interventions
Intervention 1: Intervention group: In this group, patients will simultaneously receive the four-drug regimen of Helicobacter pylori, including omeprazole 20 mg, amoxicillin 500 mg, metronidazole 500
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 18 years old All patients were diagnosed with gastric metaplasia
Exclusion criteria
Exclusion criteria: Patients with malignancy Patients who had been treated with regular nonsteroidal anti-inflammatory drugs (NSAIDs), proton-pump inhibitors, bismuth salts, or antibiotics within two weeks before endoscopy heart failure renal dysfunction pregnancy liver cirrhosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric metaplasia alleviation. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: endoscopy and biopsy result.;Helicobacter pylori eradication. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: endoscopy and biopsy result. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of dyspepsia symptoms. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Dyspepsia symptom assessment questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Fallahnia
Shahid Beheshti University of Medical Sciences
Outcome results
None listed