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The effects of evening primrose oil in preparing the cervix before hysteroscopic surgeries

Comparison of the effect of misoprostol and evening primrose oil on cervical dilatation before hysteroscopic surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230404057817N1
Enrollment
120
Registered
2023-05-08
Start date
2023-06-05
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysteroscopy.

Interventions

Intervention 1: Intervention group: In patients of this group, 2 capsules of 500 mg evening primrose oil ( Abidi Pharmaceutical Company) are placed in the posterior fornix of the vagina by the residen

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Menopausal women or women of reproductive age with no history of normal vaginal delivery (NVD) Closure of the cervix

Exclusion criteria

Exclusion criteria: Women with cervical structural abnormalities and a history of cervical insufficiency Women with Müller malformations Women with a history of conization Women with any contraindications to EPO or misoprostol (EPO or misoprostol contraindications such as seizures, asthma, high blood pressure, glaucoma, etc.) Women who have a history of failed hysteroscopy or D&C due to severe cervical stenosis.

Design outcomes

Primary

MeasureTime frame
The time to reach the required dilatation (3 to 7 mm). Timepoint: From the start of the operation until reaching the required expansion. Method of measurement: Clinical.

Secondary

MeasureTime frame
Cervical rupture. Timepoint: Immediately after the patient regains consciousness. Method of measurement: Clinical observations.;Perforation of the uterus. Timepoint: Immediately after the patient regains consciousness. Method of measurement: Clinical observations.;Side effects. Timepoint: Immediately after the patient regains consciousness. Method of measurement: Clinical observations.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarkhondeh Ghavampour

Qazvin University of Medical Sciences

mahdieghavampoor@yahoo.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026