Intrathecal injection of fentanyl and sufentanil in combination with bupivacaine in onset, duration and quality of painless labor. Complication of labor and delivery, unspecified
Conditions
Interventions
Intervention 1: Intervention group1: In sterile conditions, a 25-size needle (B.Brown company)will be entered into the intraspinal space through lumbar vertebrae L3-L4 or L4-L5, and after ensuring the
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Primiparous or multiparous pregnant mothers with term pregnancy Single fetus American Society of Anesthesiologists' (ASA) classification I, II In the advanced stage of labor with cervical dilation at least 5 centimeter in Primiparous and at least 4 centimeter in multiparous mothers Age more than 18 years Tending to have painless labor
Exclusion criteria
Exclusion criteria: Refusal to participate in the study by pregnant mothers Obesity Endocrine disease Drug abuse Allergy to study drugs Regional anesthesia contraindications such as coagulopathy, high intracranial pressure and infection of injection site .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean time of onset of sensory block. Timepoint: At zero, 5, 10, 15, 30, 45, 60, 90, 120 and 150 minutes after injection. Method of measurement: Pinprick response in both lower limbs.;Mean time of duration of sensory block. Timepoint: At zero, 5, 10, 15, 30, 45, 60, 90, 120 and 150 minutes after injection. Method of measurement: Pinprick response in both lower limbs.;The state of motor block. Timepoint: At zero, 5, 10, 15, 30, 45, 60, 90, 120 and 150 minutes after injection. Method of measurement: Bromage test: zero (full flexion of knees and ankles), one (ability to move only knees), two (ability to move only legs), and three (inability to move knees and feet).;Labor pain score. Timepoint: At zero, 5, 10, 15, 30, 45, 60, 90, 120 and 150 minutes after injection. Method of measurement: Based on visual analog scale as 1-10.;Satisfaction status of pregnant mothers with the quality of analgesia. Timepoint: After transferring pregnant mothers to recovery and stabilization of vital signs. Method of measurement: Numerical Rating (NRS) based on percentage. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug complications: (Blood pressure drop more than 20% of baseline, itching, chills, nausea and vomiting, cases leading to cesarean section). Timepoint: The duration of the procedure. Method of measurement: Observance. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamaneh Ghazanfar Tehran
Rasht University of Medical Sciences
Outcome results
None listed