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Cancer treatment using electrical pulses and chemotherapy agent

Investigating the effectiveness of electrochemotherapy in the treatment of squamous cell carcinoma and sarcoma and comparing the quality of life before and after treatment.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230403057807N1
Enrollment
120
Registered
2023-10-12
Start date
2023-11-22
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Patients with stage 4 sarcoma cancer. Condition 2: Patients with stage 4 Squamous cell carcinoma cancer. Kaposi's sarcoma of skin Squamous cell carcinoma of skin of scalp and neck

Interventions

Intervention 1: Intervention group: patients with squamous cell tumors with intravenous injection of bleomycin and electrochemotherapy. In this intervention, chemotherapy drug bleomycin is injected in

Sponsors

Bagheiat-allah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1- The patient has an accessible tumor (preferably SCC sarcoma). 2- the patient is not responding to standard treatments. 3- the patient does not have comorbidity diseases such as metal chips, platinum, and other metals in the scope of treatment. 4-2 oncologists consider this type of treatment necessary for the patient.

Exclusion criteria

Exclusion criteria: The patient have metal chips, platinum and other metals near the condition of treatment.

Design outcomes

Primary

MeasureTime frame
Tumor volume. Timepoint: Before treatment, one month, three and six months after treatment. Method of measurement: MRI imaging.;Life quality. Timepoint: before and after treatment. Method of measurement: EORTC QLQ-C30 questionnaire (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Shankayi

Bagheiat-allah University of Medical Sciences

z.shankayi@gmail.com+98 21 6689 2058

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026