Efficacy of Leukocyte-and Platelet-Rich Fibrin on Bone Regeneration after Surgical Treatment of Bilateral Mandibular Fracture

Triple-Blinded Controlled Clinical Trial Evaluating Efficacy of Leukocyte-and Platelet-Rich Fibrin on Bone Regeneration using CT scan after Surgical Treatment of Bilateral Mandibular Fracture

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230331057791N1

Enrollment

Registered

2023-05-01

Start date

2023-05-21

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bilateral Mandibular Fracture. S02. 6

Interventions

Intervention 1: In the treatment group, mandibular fracture surgery will be performed with open reduction and internal fixation using miniplates and 2 mm screws (inion, Finland) with placement of L-PR

Eligibility

Sex/Gender

All

Age

17 Years to 43 Years

Inclusion criteria

Inclusion criteria: male and female patients the age range of 17-43 bilateral mandible fractures

Exclusion criteria

Exclusion criteria: Patients with immune system disorders Patients with infection in the fracture line Smoker Any disease affecting bone density Hypertensive patients Ischemic heart patients Patients taking anticoagulants

Design outcomes

Primary

Measure	Time frame
Bone Regeneration. Timepoint: 1 week- 1 month-3 months after surgery. Method of measurement: CT scan.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdis Masoudrad

Ahvaz University of Medical Sciences

masoudrad.m@ajums.ac.ir98613376865

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026