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effect of anti-glaucoma agents on intra ocular pressure Spikes after intravitreal bevacizumab injection in patients

Investigating the prophylactic effect of antiglaucoma drugs on eye pressure in patients undergoing intravitreal injection of bevacizumab

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230330057787N1
Enrollment
108
Registered
2023-09-04
Start date
2023-09-23
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye pressure of patients undergoing intravitreal injection of bevacizumab. Glaucoma secondary to drugs

Interventions

Intervention 1: Intervention group: In the first group, 0.5% topical timolol drops (2 drops with a 10-minute interval, 60-90 minutes before the intervention) are prescribed. Intervention 2: Interventi

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1- Age more than 18 years 2- Informed and free consent to participate in the study 3- Patients who will have the first intra-boasizomat injection.

Exclusion criteria

Exclusion criteria: 1- History of retinal surgery. 2- Rupture of the posterior capsule 3- High eye pressure or glaucoma 4- Use of topical medication (such as IOP-lowering medications and corticosteroids) 5- Active intraocular inflammation 6- Eye pathologies such as pterygium or corneal opacities that can affect the evaluation of study variables 7- Withdrawal from the study during research for any reason

Design outcomes

Primary

MeasureTime frame
Intraocular pressure. Timepoint: The beginning of the study / one minute after injection / 30 minutes after injection / 24 hours after injection. Method of measurement: At the beginning of the study, 30 minutes after the injection and 24 hours after the injection, the intraocular pressure is measured with a Goldman tonometer and one minute after the injection with Tonopen.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMr. Dr. Mohammad Erish

Zahedan University of Medical Sciences

ALzahra_eyecenter@yahoo.com+98 54 3321 9915

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026