rejuvenation. Other specified disorders of the skin and subcutaneous tissue
Conditions
Interventions
Intervention 1: Intervention group: The group who receive 3% of HA and supernatant of ADSC, one time, subdermal injection at one side of the face in the laugh line. Intervention 2: Control group: grou
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: Male and female, age about 35 to 65 years old Having no anatomic disorder in face Candidate with mild to moderate wrinkles according to Glogue scale 2-4 Normal mental health based on the self assesment Having a good cooperation with research team
Exclusion criteria
Exclusion criteria: Heavy smokers or drinkers Applying skin rejuvination intervention in face at past 6 months or during the study Having a mental disorder based on the self assesment Candidate with wrinkles according to Glogue scale 1 and 5 Having an obsessed disorder Having any related skin disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantity of nasolabial fold wrinkle - Extension. Timepoint: Before the injection and after 1 and 3 months. Method of measurement: Biometry with visioface & skin sonography.;Quality of nasolabial fold wrinkle - deep. Timepoint: Before the injection and after 1 and 3 months. Method of measurement: Visio face and skin sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin elastisity. Timepoint: Before the intervention, 1 and 3 months. Method of measurement: Skin sonography.;Melanin level in skin. Timepoint: Before the intervention, 1 and 3 months. Method of measurement: Biometry with colorimeter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahsa Mollapour
Tehran University of Medical Sciences
Outcome results
None listed