Comparative study of the combined effect of black cohosh and misoprostol on the rippening cervix prior to hysteroscopy in postmenopausal women

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230318057754N1

Enrollment

Registered

2024-01-24

Start date

2024-03-10

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopause. Disorders of endocrine glands in diseases classified elsewhere

Interventions

Intervention 1: Intervention group: 6-8 hours before the operation, in addition to 200 micrograms of misoprostol (Samisaz Pharmaceutical Company), they will receive 80 mg of black cohosh (Faculty of T

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Post-menopausal women who, according to the definition, have passed their last period for more than 1 year and are candidates for elective hysteroscopy due to post-menopausal bleeding (polyp, myoma or endometrial thickening).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Cervix rippening. Timepoint: Before and after surgery. Method of measurement: Patient response based on Visual Analogue Scale (VAS) score.;Complications of hysteroscopy including bleeding and pain. Timepoint: Before and after surgery. Method of measurement: Patient response based on Visual Analogue Scale (VAS) score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAthena Behforouz

Shahid Beheshti University of Medical Sciences

dean.medicalschool@sbmu.ac.ir+98 21 23871

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026