Effect of Dexamethasone on the severity of postoperative pain, sleep quality in patients after total knee arthroplasty

Comparison of the effectiveness of high and low dose Dexamethasone intravenous injection on the severity of postoperative pain, sleep quality in patients after total knee arthroplasty

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230316057742N1

Enrollment

Registered

2023-04-24

Start date

2023-03-21

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total knee arthroplasty.

Interventions

Intervention 1: Control group: Patients of this group receive a dose of 4 mg of intravenous dexamethasone during surgery. Intervention 2: First Intervention group: Patients of this group receive a dos

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age : 18 years and above

Exclusion criteria

Exclusion criteria: Any history of diabetes and taking antidiabetic medicines

Design outcomes

Primary

Measure	Time frame
Pain intensity score based on visual analogue scale, Sleep quality score based on Saint Mary's questionnaire. Timepoint: The sleep quality questionnaire is completed once the day before the operation and once again two weeks after the surgery, The intensity of pain is measured once the day before the operation and then after the end of the spinal anesthesia every four hours until 48 hours after the surgery based on the Visual Analogue Scale. Method of measurement: Sleep quality based on Saint Mary's questionnaire, Pain intensity based on Visual Analogue Scale.	—

Measure

Time frame

Pain intensity score based on visual analogue scale, Sleep quality score based on Saint Mary's questionnaire. Timepoint: The sleep quality questionnaire is completed once the day before the operation and once again two weeks after the surgery, The intensity of pain is measured once the day before the operation and then after the end of the spinal anesthesia every four hours until 48 hours after the surgery based on the Visual Analogue Scale. Method of measurement: Sleep quality based on Saint Mary's questionnaire, Pain intensity based on Visual Analogue Scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Khalilizad

Babol University of Medical Sciences

m.khalilzad@mubabol.ac.ir+98 11 3225 2071

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026