Effects of Thymex supplement syrup on autism symptoms in autistic children

Therapeutic effects of Thymex supplement syrup on autism symptoms and blood levels of inflammatory markers in autistic children

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230314057720N1

Enrollment

Registered

2023-07-12

Start date

2023-07-23

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism. Asperger's syndrome

Interventions

Intervention 1: Intervention group: There are two types of Thymex syrup of Iran Darouk brand available in Iran, and for this study, we consider Thymex syrup of 140 ml Each 100 ml of Thymex Syrup conta

Eligibility

Sex/Gender

All

Age

3 Years to 10 Years

Inclusion criteria

Inclusion criteria: Children with autism in the age range of 3 to 10 years

Exclusion criteria

Exclusion criteria: The presence of drug interactions The presence of other diseases at the same time as autism Non-acceptance of the patient in taking medication regularly Non-cooperation of the patient in taking medication regularly

Design outcomes

Primary

Measure	Time frame
Stereotyped behaviors of children with autism. Timepoint: Evaluation of stereotyped behaviors of children with autism before the start of the intervention and 30 days after the start of taking Thymex supplement syrup. Method of measurement: Gilliam's Autism Questionnaire.;Communication in children with autism. Timepoint: Evaluation of communication in children with autism before the start of the intervention and 30 days after the start of Thymex supplement syrup. Method of measurement: Gilliam's Autism Questionnaire.;Social interactions in children with autism. Timepoint: Evaluation of social interactions in children with autism before the start of the intervention and 30 days after the start of taking Thymex supplement syrup. Method of measurement: Gilliam's Autism Questionnaire.;Developmental disorders in children with autism. Timepoint: Evaluation of developmental disorders in children with autism before the start of the intervention and 30 days after the start of taking Thymex supplement syrup. Method of measurement: Gilliam's Autism Questionnaire.;Interleukin-1 beta inflammatory factor levels. Timepoint: Measurement the level of the inflammatory factor interleukin-1 beta in children with autism before the intervention and 30 days after the start of Thymex supplement syrup. Method of measurement: Measurement the level of the inflammatory factor interleukin-1 beta using an ELISA kit.;TNF-alpha inflammatory factor level. Timepoint: Measurement the level of the inflammatory factor TNF-alpha in children with autism before the intervention and 30 days after the start of Thymex supplement syrup. Method of measurement: Measurement of TNF-alpha inflammatory factor level using ELISA kit.;Malondialdehyde level. Timepoint: Measurement the level of malondialdehyde in children with autism before the intervention and 30 days after the start of Thymex supplement syrup. Method of measurement: Measurement the level of malondialdehyde using an ELISA kit.;Total antioxidant capacit	—

Measure

Time frame

Stereotyped behaviors of children with autism. Timepoint: Evaluation of stereotyped behaviors of children with autism before the start of the intervention and 30 days after the start of taking Thymex supplement syrup. Method of measurement: Gilliam's Autism Questionnaire.;Communication in children with autism. Timepoint: Evaluation of communication in children with autism before the start of the intervention and 30 days after the start of Thymex supplement syrup. Method of measurement: Gilliam's Autism Questionnaire.;Social interactions in children with autism. Timepoint: Evaluation of social interactions in children with autism before the start of the intervention and 30 days after the start of taking Thymex supplement syrup. Method of measurement: Gilliam's Autism Questionnaire.;Developmental disorders in children with autism. Timepoint: Evaluation of developmental disorders in children with autism before the start of the intervention and 30 days after the start of taking Thymex supplement syrup. Method of measurement: Gilliam's Autism Questionnaire.;Interleukin-1 beta inflammatory factor levels. Timepoint: Measurement the level of the inflammatory factor interleukin-1 beta in children with autism before the intervention and 30 days after the start of Thymex supplement syrup. Method of measurement: Measurement the level of the inflammatory factor interleukin-1 beta using an ELISA kit.;TNF-alpha inflammatory factor level. Timepoint: Measurement the level of the inflammatory factor TNF-alpha in children with autism before the intervention and 30 days after the start of Thymex supplement syrup. Method of measurement: Measurement of TNF-alpha inflammatory factor level using ELISA kit.;Malondialdehyde level. Timepoint: Measurement the level of malondialdehyde in children with autism before the intervention and 30 days after the start of Thymex supplement syrup. Method of measurement: Measurement the level of malondialdehyde using an ELISA kit.;Total antioxidant capacit

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRayehe Reisi

Shahre-kord University of Medical Sciences

reisirayehe@gmail.com+98 31 3270 9027

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026