Comparison of Pidrolax and Sepipic Regimen with Sepipic Regimen in Bowel Preparation for Colonoscopy

Investigation of the effectiveness of the Pidrolax and Sepipic regimen compared to the Sepipic regimen in improving bowel preparation in candidate patients for colonoscopy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230314057717N4

Enrollment

944

Registered

2026-05-11

Start date

2026-05-20

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bowel preparation before colonoscopy. Encounter for screening for malignant neoplasm of colon

Interventions

Intervention 1: Intervention group: Patients in this group will receive two bottles of Peydrolax solution plus three 16-gram sachets of Sepipic powder for bowel preparation before colonoscopy. First,

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Anemia in men postmenopausal women Chronic gastrointestinal symptoms related to the bowel Abnormal gastrointestinal findings in abdominal imaging Unexplained significant weight loss Positive Fecal Immunochemical Test

Exclusion criteria

Exclusion criteria: Pregnancy or lactation Severe comorbidities (advanced heart, kidney, or liver failure) Known allergy or sensitivity to study medications Severe gastrointestinal disorders (e.g., intestinal obstruction, severe stricture, perforation, active inflammatory bowel disease) Inability to follow instructions End-stage renal disease

Design outcomes

Primary

Measure	Time frame
Quality of bowel preparation. Timepoint: Assessment of bowel preparation quality during colonoscopy. Method of measurement: Assessment by the gastroenterologist using the Boston Bowel Preparation Scale.	—

Secondary

Measure	Time frame
Time required for cecal intubation. Timepoint: Measurement during colonoscopy. Method of measurement: Time recording by the gastroenterologist using the colonoscopy device and a stopwatch.;Withdrawal time of the colonoscope after reaching the cecum. Timepoint: Measurement during colonoscopy. Method of measurement: Time recording by the gastroenterologist using the colonoscopy device and a stopwatch.;Total duration of colonoscopy. Timepoint: Measurement during colonoscopy. Method of measurement: Time recording by the gastroenterologist using the colonoscopy device and a stopwatch.;Adverse effects related to the bowel preparation regimen. Timepoint: Assessment from the initiation of bowel preparation until colonoscopy. Method of measurement: Patient self-report questionnaire and recording of adverse effects by the researcher.	—

Measure

Time frame

Time required for cecal intubation. Timepoint: Measurement during colonoscopy. Method of measurement: Time recording by the gastroenterologist using the colonoscopy device and a stopwatch.;Withdrawal time of the colonoscope after reaching the cecum. Timepoint: Measurement during colonoscopy. Method of measurement: Time recording by the gastroenterologist using the colonoscopy device and a stopwatch.;Total duration of colonoscopy. Timepoint: Measurement during colonoscopy. Method of measurement: Time recording by the gastroenterologist using the colonoscopy device and a stopwatch.;Adverse effects related to the bowel preparation regimen. Timepoint: Assessment from the initiation of bowel preparation until colonoscopy. Method of measurement: Patient self-report questionnaire and recording of adverse effects by the researcher.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Mahabadi

Shahid Beheshti University of Medical Sciences

z.mahabadi313@gmail.com+98 21 2243 2526

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026