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The effect of pancratic enzyme replacement therapy on anthropometric criteria in children with failure to thrive

The effect of pancratic enzyme replacement therapy on anthropometric criteria in children with failure to thrive : A randomized controlled clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230313057703N1
Enrollment
60
Registered
2023-06-18
Start date
2023-06-22
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Failure To Thrive in Child. Other lack of expected normal physiological development

Interventions

Intervention 1: Intervention group: The intervention group received the following routine treatment: All the studied children received routine treatment in the form of daily zinc 0.3 mg/kg body weight

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 14 Years

Inclusion criteria

Inclusion criteria: 2-14-year-old patients with failure to thrive whose Z-SCORE weight is below -2.

Exclusion criteria

Exclusion criteria: type 3 failure to thrive Type 2 growth disorder that hormonal problems have not been ruled out by an endocrinologist. cardiovascular diseases pulmonary diseases malabsorption Pancreatic exocrine insufficiency steatorrhea renal diseases

Design outcomes

Primary

MeasureTime frame
Weight gain. Timepoint: At the beginning and 2 months after. Method of measurement: Weight is measured by a Seca scale (Germany) [this scale is calibrated every day], then the patients will be treated for 2 months and re-examined with the same scale.

Secondary

MeasureTime frame
Height raise. Timepoint: at the beginning and 2 months after. Method of measurement: Height is measured by a tape measure from Seka (Germany), standing without shoes and attached to the wall at the beginning and 2 months after treatment.;BMI raise. Timepoint: at the beginning and 2 months after. Method of measurement: BMI is calculated by dividing weight in kilograms by height in square meters.;Z score raise. Timepoint: at the beginning and 2 months after. Method of measurement: By putting weight, height, and BMI in the Medscape calculator software, the Z SCORE number is reported.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShohreh Maleknejad

Rasht University of Medical Sciences

maleknejadshohreh@yahoo.com+98 13 3336 9002

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026