Effect of Propolis-Nigella sativa extract on primary tooth pulp

Evaluating the histopathology of primary teeth pulp after direct pulp capping by Nano-emulsion containing Propolis and Nigella-sativa: ?Randomized Clinical Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230312057689N1

Enrollment

Registered

2023-04-02

Start date

2023-04-21

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulpitis (pulp capping). Pulpitis

Interventions

Intervention 1: Intervention group: According to the randomization code, cavity preparation will be accomplished on one of the mandibular canine (left or right) until pulp exposure would occur. Therea

Eligibility

Sex/Gender

All

Age

6 Years to 9 Years

Inclusion criteria

Inclusion criteria: 6-9 years old without any systemic disorder no allergy to dental anesthesia two existing mandibular canine required to be extracted due to orthodontic reason the patient and his/her parents are eager to participate in the study

Exclusion criteria

Exclusion criteria: the mentioned canine teeth have root resorption more than apical third the mentioned canine have irreversible pulpitis

Design outcomes

Primary

Measure	Time frame
Percentage of dentine bridge formation. Timepoint: two months after intervention. Method of measurement: optical microscope.	—

Secondary

Measure	Time frame
The intensity of the presence of inflammatory cells. Timepoint: two months after intervention. Method of measurement: optical microscope.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaeze Hamze

Shahed University

faeze.hamze@gmail.com+98 21 8895 9210

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026