Adult malnutrition. Mild protein-calorie malnutrition
Conditions
Interventions
Intervention 1: Intervention group: Receive weight gain diet (500 kcal more than daily requirement), multivitamin and probiotic supplement (containing 109 CFU/capsule, lactobacillus with maltodextrin,
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Healthy Adults 18 to 65 years old Body mass index less than 18.5 kg/m2 Consent to participate in the study by signing the informed consent form Provision of written informed consent
Exclusion criteria
Exclusion criteria: Smoking or alcohol consumption Pregnancy or lactation History of antibiotics or probiotic supplements or consumption of foods containing probiotics within three months before commencement of this study. Regular consumption of foods containing probiotics History of chronic diseases such as inflammatory bowel disease (IBD), liver disease, kidney disease, cancer, diabetes, or irritable bowel syndrome Taking drugs that affect appetite or body weight
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body mass index. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: Formula (weight/height squared). | — |
Secondary
| Measure | Time frame |
|---|---|
| Waist circumference and hip circumference. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: Tape meter.;Medial arm circumference (MUAC). Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: Tape meter.;Complete blood count (CBC-RDW). Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: Biochemical analysis of blood sample.;Body composition (fat mass, fat-free mass, lean body mass, skeletal muscle index, total body water content, basal metabolic rate). Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: Bioelectric Impedance Analysis (BIA) device.;Phase angle. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: Bioelectric Impedance Analysis (BIA) device.;Appetite. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: Visual analog scales (VAS).;Dietary intake. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: 3-day 24-hour recall.;Blood pressure. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: Digital pressure gauge.;Stool consistency status. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the start of probiotic consumption. Method of measurement: Bristol stool chart.;Body weight. Timepoi | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Hatami
Mashhad University of Medical Sciences
Outcome results
None listed