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Efficacy of Hyaluronic acid filler injection in Perioral lesions of Scleroderma patients

Efficacy of Hyaluronic acid filler injection in Perioral lesions of Scleroderma patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230308057658N1
Enrollment
15
Registered
2024-10-25
Start date
2024-10-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scleroderma disease. Systemic sclerosis

Interventions

Intervention group: 15 patients with scleroderma will be included in the study, according to the diagnostic criteria of systemic sclerosis in 2013, the patients will be included in the study after eva

Sponsors

Espad Pharmed
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Suffering from Systemic sclerosis according to the 2013 criteria Age 70-18 Female sex According to the rheumatologist, the disease is in remission

Exclusion criteria

Exclusion criteria: Pregnancy Breastfeeding BMI<17

Design outcomes

Primary

MeasureTime frame
Viscoelasticity. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: TEWAMETER probe.;Skin surface hydration. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: Corneometer probe.;The maximum amount of mouth opening. Timepoint: At the beginning of the study, 1 and 3 months after injection. Method of measurement: Digital caliper.;The distance between the upper and lower front teeth. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: Digital caliper.;Intercommissural distance. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: Digital caliper.;Upper and lower lip thickness. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: Digital caliper.;Dryness of skin. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: Ask the patient.;Pain when opening the mouth. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: Ask the patient.;Overall satisfaction with treatment. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: Ask the patient.;The degree of skin elasticity improvement after treatment. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: Ask the patient.;Transepidermal water loss. Timepoint: At the beginning of the study, 1 and 3 months after the injection. Method of measurement: Cutometer probe.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactvahide sadat lajevardi

Tehran University of Medical Sciences

vahide_lajevardi@yahoo.com+98 21 5288 8282

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026