Determining the effect of venous magnesium on improving the quality of anesthesia

Determining the effect of venous magnesium on improving the quality of anesthesia in patients undergoing appendectomy under spinal anesthesia

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230307057651N1

Enrollment

Registered

2023-05-03

Start date

2023-04-01

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Appendicitis. Condition 2: pain. Condition 3: nausea and vomiting. Acute appendicitis Pain, unspecified Nausea and vomiting

Interventions

Intervention 1: Intervention group: Patients in the intervention group in the study will receive magnesium sulfate at the rate of 50 mg per kilogram of body weight intravenously before the operation

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age 18 to 50 years, acute appendicitis patients

Exclusion criteria

Exclusion criteria: History of drug abuse, alcohol consumption, recent use of tranquilizers, stimulants and antipsychotics, antihypertensive drugs, calcium channel blockers, and history of neuromuscular diseases, thyroid disorders, history of any type of kidney and heart disease.

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Pain measurement at 1, 3, 6, 12 and 18 hours after surgery. Method of measurement: The measurement of patients' pain will be based on the criteria for measuring patients pain with 'Visual Analogue Scale.Zero point is equal to not having any pain and 10 is the most severe possible pain.	—

Secondary

Measure	Time frame
Nausea and vomiting. Timepoint: 3 and 12 hours after surgery. Method of measurement: Based on a qualitative review by the following method:1- No nausea and vomiting 2- Nausea 3- Nausea and vomiting one to two times 4- Nausea and vomiting more than 2 times.;Anxiety and restlessness. Timepoint: 3, 6, 12, 18 hours after surgery. Method of measurement: According to Ramsey scale (0 to 5): 0 (restless), 1 (calm and alert), 2 (sleepy), 3 (confused but responding to verbal commands), 4 (no response to verbal commands), 5 (absence) response to provocations)).;Consent of the surgeon. Timepoint: During surgery. Method of measurement: has / does not have.	—

Measure

Time frame

Nausea and vomiting. Timepoint: 3 and 12 hours after surgery. Method of measurement: Based on a qualitative review by the following method:1- No nausea and vomiting 2- Nausea 3- Nausea and vomiting one to two times 4- Nausea and vomiting more than 2 times.;Anxiety and restlessness. Timepoint: 3, 6, 12, 18 hours after surgery. Method of measurement: According to Ramsey scale (0 to 5): 0 (restless), 1 (calm and alert), 2 (sleepy), 3 (confused but responding to verbal commands), 4 (no response to verbal commands), 5 (absence) response to provocations)).;Consent of the surgeon. Timepoint: During surgery. Method of measurement: has / does not have.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Deldadeh Moghaddam

Ardabil University of Medical Sciences

d.mina15@yahoo.com+98 45 3325 7086

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026