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Efficacy of 12- and 24-hour Magnesium Sulfate in Preterm Infants

Comparison of the Effectiveness of 12- and 24-hour Magnesium Sulfate in Preterm infants at Afzalipour Hospital in 2015-2016

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230307057644N3
Enrollment
190
Registered
2026-01-30
Start date
2026-01-29
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm birth. Preterm [premature] newborn [other]

Interventions

Intervention 1: Intervention group: Mothers in the First Group Will Receive 4 Grams of Magnesium Sulfate Over 20 Minutes as a Loading Dose, which will Continue at 1 gram per Hour for 12 Hours. Interve

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Preterm Pregnant Mothers Preterm Pregnant Mothers who took Beta

Exclusion criteria

Exclusion criteria: Major Fetal Anomalies Intrauterine Fetal Death Second Stage of Labor Recent Receipt of Magnesium Sulfate and Any Tocolytics other Than Magnesium Sulfate (Including Indomethacin) Mothers Who Did Not Receive Betamethasone for Fetal Lung Maturation Mothers Who Have Contraindications to Receiving Sulfate, Including Chronic Maternal Kidney and Liver Disease or Electrolyte Disorders. Absence of Patellar Reflex, Urine Output below 100 per Hour in the Mother

Design outcomes

Primary

MeasureTime frame
Preterm birth. Timepoint: 6 Months. Method of measurement: Assessing the "well-being" of newborns with Apgar scores at 1, 5, and 10 minutes, Presence or absence of intraventricular hemorrhage, Moore's reflex, Reflex routing, Sucking reflex, Normal arterial blood gases at birth, pH above 7.2, BE less than 12.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGhazal Mansouri

Kerman University of Medical Sciences

mansori@kmu.ac.ir+98 34 3132 8000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026