Condition 1: Platelet-Rich Fibrin. Condition 2: Photobiomodulation.
Conditions
Interventions
Intervention 1: Intervention group: The nurse takes 10 ml of a blood sample from the median cubital vein of each patient and puts it in a dry test tube without anticoagulant. Then, they will be centr
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 18 Years of Age Referring to the Special Clinic of the Sari Dental Faculty who have Extensive Irreparable Caries, Failed Root Canal Therapy, Periodontal Disease, Tooth Fracture, Indications for Extraction of Anterior Teeth and Premolars (Maxilla and Mandible) Intact Surrounding Alveolar Bone (Remaining Bone at least Two-Thirds of the Root Length) Tooth Socket with Four Healthy Walls after Extraction Patients Who Willing to Participate in the Study Teeth that Do not Require Surgical Methods to Remove and Do not Require Using of Surgical Burs Patients Who have the Ability to Participate in Examinations and Follow-up ASA I-II Patinets
Exclusion criteria
Exclusion criteria: Patients with Poor Oral Hygine Pregnant or Lactating Women or Patients Who are Planning to Get Pregnant Smokers (More than ten Cigarettes per Day) and Alcoholism Patients with Uncontrolled Systemic Disease and History of Head and Neck Radiotherapy and Weak Immune System Chronic Treatment with Any Drug that Affects Bone Function: Heparin, Cyclosporine, Bisphosphonate, Chemotherapy Drugs Presence of Periapical or Periodontal Considerable Lesions around the Corresponding Teeth and Presence of Dehiscence and Fenestration in the Buccal Bone Plate Contraindications for Tooth Extraction Allergy to Any of the Study Products A Severe Acute lnfection or Any Other Factor that Limits the Opening of the Mouth
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vertical height of alveolar ridge. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after tooth extraction. Method of measurement: Cone Beam CT Scan.;Buccolingual width of alveolar ridge. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after tooth extraction. Method of measurement: Cone Beam CT Scan.;Soft tissue healing. Timepoint: 2, 7 and 14 days after tooth extraction. Method of measurement: Modified soft tissue healing index.;Keratinized gingival width. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after tooth extraction. Method of measurement: Periodontal probe.;Pain. Timepoint: 24, 48 and 72 hours after tooth extraction. Method of measurement: Visual Analogue Scale.;Bone density. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after tooth extraction. Method of measurement: ?Fractal analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAvideh Maboudi
Mazandaran University of Medical Sciences
Outcome results
None listed