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Effect of hydro-alcoholic extract of jaft on the healing of 2nd degree burn

Evaluating the effectiveness of the cream prepared from the hydro-alcoholic extract of internal layer of oak fruit (jaft) on wound healing in patients with 2nd degree burns

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230304057615N2
Enrollment
30
Registered
2025-01-19
Start date
2024-12-21
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

2nd degree burn wounds. burn

Interventions

Intervention 1: Control group: In the control group, 1% silversulfadiazine ointment will be placed directly on all the patients wounds by a plastic surgeon and bandaged. The wounds of all patients who

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to No maximum

Inclusion criteria

Inclusion criteria: Age more than 8 years The interval between the start of treatment and the occurrence of burns should be less than 24 hours. Suffering from 2nd degree burns and the amount of superficial skin burns should be less than 20%. Being alert and having the ability to communicate verbally Patients whose body mass index is more than 18.5 and less than 30.

Exclusion criteria

Exclusion criteria: Patients with mental disorders Patients whose burns are caused by electricity, chemicals, inhalation or self-immolation. Patients who do not want to cooperate at the beginning of the intervention or during the intervention. Patients suffering from severe respiratory diseases or asthma and allergic diseases or showing allergic symptoms to the treatment. Patients with a history of metabolic diseases, coagulation disorders, immunodeficiency, vascular, diabetes, kidney failure Patients who are undergoing treatments that change the state of wound healing (such as corticosteroids, chemotherapy, radiotherapy) Women who are pregnant or breastfeeding. Patients with head and neck burns Infection of patients' wounds during research Patients who are active or inactive smokers.

Design outcomes

Primary

MeasureTime frame
The extent of the wound. Timepoint: Before starting the intervention and then every 5 days until the wound heals. Method of measurement: ruler.;The time it takes for the wound to heal. Timepoint: Before starting the intervention and then every 5 days until the wound heals. Method of measurement: The clinical diagnosis of a plastic surgery doctor based on the reepithelialization of more than 95% of the wound surface.

Secondary

MeasureTime frame
Microbial culture from the wound surface. Timepoint: Before the intervention and the fifth day and 20th day. Method of measurement: Swab sampling from the wound bed and its culture in the laboratory.;Intensity of pain. Timepoint: before the start of the intervention and then on the fifth day, the tenth day and then with 10-day intervals until the wound heals. Method of measurement: VAS questionnaire --- HUSKISSON, Edward C. Measurement of pain. The lancet, 1974, 304.7889: 1127-1131.?.;Intensity of itching. Timepoint: before the start of the intervention and then on the fifth day, the tenth day and then with 10-day intervals until the wound heals. Method of measurement: Burns itch questionnaire --- VAN LOEY, N. E., et al. Validation of the burns itch questionnaire. Burns, 2016, 42.3: 526-534.?.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Mohammad Zamani

Ahvaz University of Medical Sciences

amirmd742@gmail.com0986134450358

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026