Gastroesophageal reflux. Gastro-esophageal reflux disease without esophagitis
Conditions
Interventions
Intervention 1: Intervention group :First, the oaks of the Quercus Persica species will be collected from the forests of the Zagros mountains in Mal Agha village, Baghmelk city, Khuzestan province, an
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients who are between 20 and 60 years old Diagnosed with gastroesophageal reflux (GERD) based on clinical symptoms (having reflux at least twice a week), diagnostic endoscopy (esophagogastroduodenoscopy) and the Los Angeles classification (grades A to D) Not taking PPI for at least 1 week before entering the study
Exclusion criteria
Exclusion criteria: Patients who are infected with H. pylori in the initial diagnostic examinations and before the intervention, based on stomach biopsy or stool test Patients with coagulation disorders or GI bleeding Patients who have a history of upper GI surgery or suffer from other digestive diseases such as irritable bowel syndrome, peptic ulcer, obstructive disease, etc Patients with Zollinger-Ellison syndrome, primary motility disorders, Barrett's esophagus, esophageal stricture, and any severe disease with reflux and malignancy of the upper gastrointestinal tract, as well as pregnant or lactating women Patients who take PPIs from 28 days before diagnostic endoscopy or H2 receptor antagonists from 14 days before diagnostic endoscopy Patients who take NSAIDs or other drugs that may interfere with the interpretation of the study result. (diazepam, quinidine, Dilantin, warfarin, anticholinergics, prostaglandin analogs, or sucralfate) Patients with chronic kidney, lung, and liver diseases and ... Patients who have a history of sensitivity to pantoprazole or seasonal allergies or asthma Patients who consume alcohol or drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastroesophageal reflux score in the health-related quality of life questionnaire. Timepoint: All patients are evaluated at the beginning of the study (before the intervention) and at the end of the first, second and fourth week. Method of measurement: Health-related quality of life questionnaire (related to GERD). | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastroesophageal reflux score in frequency scale questionnaire for symptoms. Timepoint: All patients are evaluated at the beginning of the study (before the intervention) and at the end of the first, second and fourth week. Method of measurement: The frequency scale for the symptoms questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Akbar Shayesteh
Ahvaz University of Medical Sciences
Outcome results
None listed