Pediatric cirrhosis. Other and unspecified cirrhosis of liver
Conditions
Interventions
Intervention 1: Intervention group: 7-18 year old children with compensated cirrhosis who are treated with rosuvastatin in addition to standard treatment. Intervention 2: Control group: children aged
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
7 Years to 18 Years
Inclusion criteria
Inclusion criteria: All children with compensated Cirrhosis admited in Gastrointestinal and Endoscopy department of akbar hospital
Exclusion criteria
Exclusion criteria: Termination of cooperation and lack of follow-up Hypersensivity reaction to statins Pregnancy Portosystemic shunt or TIPS Acute liver failure decompensated Cirrhosis Liver transplant Statin toxicity ( myopathy,hepatopathy)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dumping criterion, splenic artery intraparenchymal blood flow resistance index, superior mesenteric artery pulsation index and renal interlobar artery resistance index in Doppler sonography, Esophageal varice grade in endoscopy, Number of variceal bleeding episodes. Timepoint: Before intervention and 6 months after intervention. Method of measurement: Damping index and vascular resistance are measured by doppler sonographic device. Varicose grade is evaluated by endoscopy and bleeding frequency is evaluated by questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Ali Kiani
Mashhad University of Medical Sciences
Outcome results
None listed