Condition 1: Fracture of upper limb. Condition 2: Fracture of lower limb. Fracture of upper limb, level unspecified Fracture of lower leg, including ankle
Conditions
Interventions
Intervention 1: Intervention group: The patients in the ketamine group will receive ketamine at a dose of 0.3mg/kg 30 minutes after the induction of anesthesia. For this purpose, the patients will und
Sponsors
Ilam University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: candidate for elective orthopedic surgery with general anesthesia and class l and ll in the ASA classification Age range from 18 to 60 years No history of opioid addiction Absence of underlying diseases such as: liver and kidney failure, history of seizures, pregnancy and breastfeeding, high ICP (intracranial pressure) and glaucoma, thyrotoxicosis, high blood pressure, diabetes, heart disease and history of disease respiratory No history of disorders such as mental retardation or psychological illness No history of drug sensitivity to pethidine or ketamine No history of chronic use of painkillers
Exclusion criteria
Exclusion criteria: opioid addiction underlying diseases such as: liver and kidney failure, history of seizures, pregnancy and breastfeeding, high ICP (intracranial pressure) and glaucoma, thyrotoxicosis, high blood pressure, diabetes, heart disease and history of disease respiratory mental retardation or psychological illness drug sensitivity to pethidine or ketamine chronic use of painkillers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score based on Visual Analogue Scale tool. Timepoint: at recovery room, 6 and 12 hours after surgery. Method of measurement: Visual Analogue Scale tools. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamed Azadi
Ilam University of Medical Sciences
Outcome results
None listed