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Compare the effect of heparin lock and normal saline flushing on central venous catheter patency in patients admitted to the intensive care unit

Compare the effect of heparin lock and normal saline flushing on central venous catheter patency in patients admitted to the intensive care unit

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230228057559N1
Enrollment
90
Registered
2023-03-07
Start date
2023-04-04
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical complications of central venous catheter in intensive care unit patients. Mechanical complication of other cardiac and vascular devices and implants

Interventions

Intervention 1: The first intervention group: In patients whose central venous catheter has been in place for less than 24 hours and who meet the conditions for entering the study, before clamping the

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All hospitalized patients over 18 years of age hospitalized in the intensive care unit who have a central venous catheter The patient's central venous catheter should be three ducts and the size of the catheter ducts should be 16, 18, 18. The patient is treated with anticoagulants Absence of obvious signs of infection at the catheter insertion site (discharge, redness, and swelling) Place the catheter in the subclavian or internal jugular vein The activated partial thromboplastin time (PTT) is within the normal range Less than 24 hours have passed since the central venous catheter was inserted At the beginning of the study, the site of catheter placement should be free of bleeding

Exclusion criteria

Exclusion criteria: Occurrence of infection symptoms at the catheter insertion site during the study Unwanted exit of the catheter from its anatomical location, for example, due to the patient's restlessness Bleeding at the catheter insertion site The patient needs cardiopulmonary resuscitation Occurrence of coagulation disorders and change of PTT outside the normal range

Design outcomes

Primary

MeasureTime frame
The duration of the opening of the central venous catheter. Timepoint: The primary outcome (catheter patency) is checked every 8 hours. The length of time the catheter remains is recorded at the end of the study or when the catheter is blocked. Method of measurement: How to set the duration of the central venous catheter open is the clock.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe Saffari Khozani

Mashhad University of Medical Sciences

Saffarike982@mums.ac.ir+98 51 3859 1511

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026