Comparison of macular detachment surgery with ILM flap in retinal hole treatment

Efficacy of Combined Internal Limiting Membrane Peeling and Macular Detachment surgery compared to Internal Limiting Membrane Peeling and Flap surgery in the treatment of Large macular hole in Isfahan city in 2023

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20230226057539N1

Enrollment

Registered

2023-05-20

Start date

2023-03-10

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular hole. Macular cyst, hole, or pseudohole

Interventions

Intervention 1: Intervention group: combined Macular detachment and Internal Limiting Membrane peeling surgery 1. D

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: Macular hole greater than 400 microns based on clinical examination and Spectral Domain Optical Coherence Tomography (SD-OCT) Macular hole (MH) in which the patient's symptoms have lasted less than 2 years Age above 50 years

Exclusion criteria

Exclusion criteria: Perform any retinal surgery or retinal laser Retinal holes due to secondary causes such as trauma Stage 1 or 2 macular holes Any disease other than Macular Hole (MH) that affects visual acuity except cataract If, for any reason, silicone oil is injected for tamponade during surgery

Design outcomes

Primary

Measure	Time frame
What is the success rate of closing the anatomical macular hole (MH) with macular detachment (MD) based on Spectral domain Optical Coherence Tomography (SD-OCT)?. Timepoint: Before surgery and 1 and 3 months after surgery. Method of measurement: The degree of success in the anatomical closure of the macular hole is expressed by SD-OCT analysis.;What is the success rate of anatomical closure of MH with Inverted Flap Of Internal Limiting Membrane Peeling (i-ILM peeling) based on SD-OCT?. Timepoint: Before surgery and 1 and 3 months after surgery. Method of measurement: The degree of success in the anatomical closure of the macular hole is expressed by SD-OCT analysis.;What is the level of visual acuity before and after MH surgery using the MD method with the help of Snellen chart and in the form of Logarithm of Minimum Angle of Resolution (LogMAR)?. Timepoint: Before surgery and 1 and 3 months after surgery. Method of measurement: Visual acuity is measured with the help of Snellen chart and is expressed based on Logarithm of Minimum Angle of Resolution (LogMAR).;What is the level of visual acuity before and after MH surgery using the i-ILM peeling method with the help of Snellen chart and LogMAR?. Timepoint: Before surgery and 1 and 3 months after surgery. Method of measurement: Visual acuity is measured with the help of Snellen chart and is expressed based on Logarithm of Minimum Angle of Resolution (LogMAR).	—

Measure

Time frame

What is the success rate of closing the anatomical macular hole (MH) with macular detachment (MD) based on Spectral domain Optical Coherence Tomography (SD-OCT)?. Timepoint: Before surgery and 1 and 3 months after surgery. Method of measurement: The degree of success in the anatomical closure of the macular hole is expressed by SD-OCT analysis.;What is the success rate of anatomical closure of MH with Inverted Flap Of Internal Limiting Membrane Peeling (i-ILM peeling) based on SD-OCT?. Timepoint: Before surgery and 1 and 3 months after surgery. Method of measurement: The degree of success in the anatomical closure of the macular hole is expressed by SD-OCT analysis.;What is the level of visual acuity before and after MH surgery using the MD method with the help of Snellen chart and in the form of Logarithm of Minimum Angle of Resolution (LogMAR)?. Timepoint: Before surgery and 1 and 3 months after surgery. Method of measurement: Visual acuity is measured with the help of Snellen chart and is expressed based on Logarithm of Minimum Angle of Resolution (LogMAR).;What is the level of visual acuity before and after MH surgery using the i-ILM peeling method with the help of Snellen chart and LogMAR?. Timepoint: Before surgery and 1 and 3 months after surgery. Method of measurement: Visual acuity is measured with the help of Snellen chart and is expressed based on Logarithm of Minimum Angle of Resolution (LogMAR).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhodayar Golabchigilani

Esfahan University of Medical Sciences

khodayar82@gmail.com+98 31 3445 2031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026