Reflux. Gastro-esophageal reflux disease
Conditions
Interventions
Intervention 1: Intervention group: Treatment with omeprazole capsules 20 mg per day. Intervention 2: Intervention group: Asvard capsule 1200 mg per day (900 cases + 300 roses). Intervention 3: Interv
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The Reflux patients with the age between 18-60 years olds. The patients have to been infected with the Reflux disease for 6 months ago and it get shown Reflux symptoms twice in the week. Reflux diagnosis would be base on ROME IV symptoms and endoscopy without specific pathological findings All subjects must be without Helicobacter pylori infection. All subjects don't have been any antibiotics and PPIs in the last month. Without underlying diseases such as heart failure; kidney and liver failure; cirrhosis; Diabetes, thyroid disorders, etc. Without cigarette smoking, drugs abuse or alcohol Without taking NSAIDs or Aspirin Without pregnancy or breastfeeding
Exclusion criteria
Exclusion criteria: If patient use a drug with a direct impact on the digestive system. If patient is infected to underlying diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of Reflux symptoms. Timepoint: Days: zero, 21, 42 and 56. Method of measurement: Questionnaires and standard measurement scales. | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigation of likely side effects after drug administration. Timepoint: Days: 21, 42 and 56. Method of measurement: Visual Analogue Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaeid Sepehrikia
Gorgan University of Medical Sciences
Outcome results
None listed