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The effect of plantago major cream on second degree burns

Studying the effectiveness of 25% plantain leaf cream on the healing process of second-degree burn wounds compared to silver sulfadiazine cream

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230225057535N2
Enrollment
70
Registered
2025-05-03
Start date
2024-01-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: burn wounds. Condition 2: burn wounds. Condition 3: burn wounds. Condition 4: burn wounds. Burn of unspecified degree of shoulder and upper limb, except wrist and hand Burn of unspecified degree of wrist and hand Burn of unspecified degree of unspecified site of lower limb, except ankle and foot Burn of unspecified degree of ankle and foot

Interventions

Intervention 1: Intervention group: They will receive Plantago major cream and it will be applied twice a day on the surface of the wound. Intervention 2: Control group: Silver sulfadiazine cream 2 t

Sponsors

Fasa University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18 to 60 years Not having any underlying disease such as diabetes, seizures, nervous and mental disorders Not using corticosteroids and immunosuppressive drugs Insensitivity to medicinal plants Absence of pregnancy and breastfeeding No underlying skin disease Having 2nd degree thermal burns Burn percentage between 5 and 25% A maximum of 48 hours have passed since the burn Burns in the upper and lower limbs

Exclusion criteria

Exclusion criteria: Drug sensitivity History of mental illnesses Pregnancy and breastfeeding History of allergy to medicinal plants Chemical and electrical burns Burns other than upper and lower limbs Occurrence of skin complications during the treatment period The patient's lack of tolerance and his lack of satisfaction with the decision to continue the treatment

Design outcomes

Primary

MeasureTime frame
Wound size, redness, inflammation, edema. Timepoint: Before starting the study, days 5, 9, 13, 17, the end of the study. Method of measurement: The size of the wound with a ruler. Inflammation, redness and edema based on the standard wound questionnaire.

Secondary

MeasureTime frame
Recovery time? wound infection. Timepoint: The healing time is measured according to the complete healing of the wound and the creation of new tissue. Infection in the days before the study and day 3, 7, 10. Method of measurement: Recovery time: observation of granulation tissue and new epithelium. The negative response to the infection was death.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahsa Rostami

Fasa University of Medical Sciences

mahsa_59_2007@yahoo.com+98 71 5335 0994

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026