None listed
Conditions
Interventions
Intervention 1: First intervention: Progesterone 400 mg vaginal suppositories manufactured by Ati Pharmed Pharmaceutical Company in Iran. Intervention 2: Second intervention: Progesterone 400 mg vagin
Sponsors
Ati Pharmed pharmaceutical company
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: A healthy, non-pregnant and non-lactating female volunteer, who at the time of drug administration should be on the 4th-6th day of her menstrual cycle so that the amount of endogenous progesterone is at its minimum. Be between 18 and 45 years old. All candidates must be non-smokers. Candidate's body mass index (BMI) should be less than 30 kg/m2.
Exclusion criteria
Exclusion criteria: Blood pressure lower than 90/60 mm Hg or higher than 140/90 mm Hg Smokers who use more than 10 cigarettes a day Consumption of any drugs, alcohol or tobacco products within 2 weeks before receiving the drug
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cmax. Timepoint: Once 15 minutes before the start of drug administration and then at time intervals: 0, 0.25, 0.5, 1, 1.5, 2, 3, 4, 6, 8, 10, 12, 24, 30, 48, 56 and 72 hours after administration. , will be done. Method of measurement: HPLC with UV detector. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMonireh Jalalipour
Nik Azma Pars Alborz laboratory
Outcome results
None listed