???? ???????? ????????? ???. Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention 1: Intervention group: N-acetyl cysteine ??ampoule at the rate of 20 mg per kilogram of body weight in Prime solution in the cardiopulmonary bypass circuit. Intervention 2: Control group:
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients candidates for CABG surgery informed consent age (40-70) years ejection fraction EF = 50%) non-emergency patients, patients with stable hemodynamics patients who did not use ECMO and balloon pump before surgery
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Troponin. Timepoint: Before surgery, immediately and eight hours after surgery. Method of measurement: Venous blood sample.;CRP. Timepoint: Before surgery, immediately and 24 hours after surgery. Method of measurement: Venous blood sample. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of stay in ICU. Timepoint: Time of discharge from ICU. Method of measurement: patient file.;Need for defibrillator shock during surgery. Timepoint: during surgery. Method of measurement: view.;The need for a pacemaker during surgery. Timepoint: during surgery. Method of measurement: view. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehran Shahzamani
Esfahan University of Medical Sciences
Outcome results
None listed