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The Effectiveness of 3MA transcranial direct current stimulation (TDCS) on cognitive function, depression, anxiety and severity of obsessive-compulsive symptoms in individuals with OCD: A randomized clinical trial

The Effectiveness of 3MA transcranial direct current stimulation (TDCS) on cognitive function, depression, anxiety and severity of obsessive-compulsive symptoms in individuals with OCD: A randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20230216057437N1
Enrollment
40
Registered
2023-03-31
Start date
2023-04-09
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-Compulsive Disorder. Obsessive-compulsive disorder

Interventions

Intervention 1: Intervention group: Twenty sessions of 20 minutes in ten days under real stimulation with an intensity of 3 milliamperes, with the anode placed on the right area of the inferior fronta

Sponsors

Zanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Having complete OCD diagnostic criteria as diagnosed by a psychiatrist and psychologist based on DSM-5 Having at least a third middle school education Age range between 18-50 years Sign the written consent Not receiving psychological treatment two months before the intervention and simultaneously with the implementation of the intervention until the follow-up period The same drug group was used along with dose adjustment

Exclusion criteria

Exclusion criteria: Risk of suicide psychosis Existence a history of seizures and epilepsy The presence of an electrical or metallic object in the body Diagnosis of any neurological conditions that affects the central nervous system. (like Parkinson's) pregnancy Comorbid bipolar disorder

Design outcomes

Primary

MeasureTime frame
The person's score on the Yale-Brown Obsessive-Compulsive Scale. Timepoint: Measuring the severity of obsessive-compulsive symptoms before the intervention, immediately after the intervention, two weeks, four weeks, and three months after the intervention as follow-up periods. Method of measurement: Yale-Brown Obsessive-Compulsive Scale.;Individual's score in Beck depression questionnaire. Timepoint: Measurement of depression levels before the intervention, immediately after the intervention, and two-week, four-week, and three-month follow-up periods after the intervention. Method of measurement: Beck depression inventory.;Individual's score in Beck's anxiety inventory. Timepoint: Measurement of anxiety levels before the intervention, immediately after the intervention, and two-week, four-week, and three-month follow-up periods after the intervention. Method of measurement: Beck's anxiety inventory.

Secondary

MeasureTime frame
The score of a person's working memory in the task of Spatial Working Memory (SWM) from Cambridge Neuropsychological Test Automated Battery (CANTAB). Timepoint: Measuring the individual's score in the task of Spatial Working Memory (SWM) before the intervention, Immediately after the end of the intervention, two weeks, four weeks, and three months after the end of the intervention as follow-up periods. Method of measurement: the Spatial Working Memory (SWM) task from CANTAB.;A person's cognitive inhibition score in the Stop Signal Task (SST) from CANTAB. Timepoint: Measuring the individual's score in the Stop Signal Task (SST) task before the intervention, Immediately after the end of the intervention, two weeks, four weeks, and three months after the end of the intervention as follow-up periods. Method of measurement: the Stop Signal Task (SST) from CANTAB.;The score of the person's cognitive flexibility in the Intra-Extra Dimensional Set Shift (IED) task from CANTAB. Timepoint: Measuring the individual's score in the Intra-Extra Dimensional Set Shift (IED) task before the intervention, Immediately after the end of the intervention, two weeks, four weeks, and three months after the end of the intervention as follow-up periods. Method of measurement: the Intra-Extra Dimensional Set Shift (IED) task from CANTAB.;A person's visual memory score in the Paired Associates Learning assignment from CANTAB. Timepoint: Measuring the individual's score in the Paired Associates Learning task before the intervention, Immediately after the end of the intervention, two weeks, four weeks, and three months after the end of the intervention as follow-up periods. Method of measurement: the Paired Associates Learning assignment from CANTAB.;The score of a person's sustained attention in the task of Rapid Visual Information Processing from CANTAB. Timepoint: Measuring the individual's score in the Rapid Visual Information Processing task before the intervention, Immediately after the en

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Fatehi chenar

Zanjan University of Medical Sciences

atefehfatehi993@gmail.com+98 24 3301 8100

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026